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Improved Synthesis of and Nucleophilic Addition to 2-Formyl-2-Cyclohexenone

A preparation of 2-formyl-2-cyclohexenone in nearly quantitative yield and purity of approximately 95% is described. It is scalable and has been extended to the synthesis of the 5- and 7-membered ring homologs with comparable yields. Conditions have also been developed for the successful conjugate a...

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Detalhes bibliográficos
Publicado no:Tetrahedron Lett
Main Authors: Adary, Elan M., Chang, Chih-wei, Auria, Damian T. D’, Nguyen, Phuc M., Polewacz, Klaudyna, Reinicke, Justin A., Seo, Hannah, Berger, Gideon O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4290381/
https://ncbi.nlm.nih.gov/pubmed/25593375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2014.11.100
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