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Acute and Chronic B Cell Depletion Disrupts CD4(+) and CD8(+) T Cell Homeostasis and Expansion during Acute Viral Infection in Mice

B cells provide humoral protection against pathogens and promote cellular immunity through diverse nonclassical effector functions. To assess B cell function in promoting T cell homeostasis, mature B cells were either acutely or chronically depleted in mice using CD20 mAb. Acute B cell depletion in...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Immunol
Prif Awduron: Lykken, Jacquelyn M., DiLillo, David J., Weimer, Eric T., Roser-Page, Susanne, Heise, Mark T., Grayson, Jason M., Weitzmann, M. Neale, Tedder, Thomas F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4290158/
https://ncbi.nlm.nih.gov/pubmed/24928986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302848
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