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CTLA4-Ig Induced T-Cell Anergy Promotes Wnt10b Production and Bone Formation
OBJECTIVE: Rheumatoid arthritis (RA) is an inflammatory autoimmune disease characterized by severe joint erosion and systemic osteoporosis. Chronic T-cell activation is a hallmark of RA and agents that target the CD28 receptor on T-cells, needed for T-cell activation, are being increasingly employed...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3994890/ https://ncbi.nlm.nih.gov/pubmed/24757150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38319 |
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