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CTLA4-Ig Induced T-Cell Anergy Promotes Wnt10b Production and Bone Formation

OBJECTIVE: Rheumatoid arthritis (RA) is an inflammatory autoimmune disease characterized by severe joint erosion and systemic osteoporosis. Chronic T-cell activation is a hallmark of RA and agents that target the CD28 receptor on T-cells, needed for T-cell activation, are being increasingly employed...

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Autors principals: Roser-Page, Susanne, Vikulina, Tatyana, Zayzafoon, Majd, Weitzmann, M. Neale
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994890/
https://ncbi.nlm.nih.gov/pubmed/24757150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38319
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