Učitavanje...
MMP9-sensitive polymers mediate environmentally-responsive bivalirudin release and thrombin inhibition
MMP9-responsive bivalirudin-HPMA copolymers were synthesized for direct, local administration in rat spinal cord contusion injury models. Polymer-conjugated bivalirudin peptides maintained activity while demonstrating enzyme-mediated release upon MMP9 exposure and prolonged release from hyaluronic a...
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| Izdano u: | Biomater Sci |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4289632/ https://ncbi.nlm.nih.gov/pubmed/25589953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4BM00259H |
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