Mitochondrial ADCK3 employs an atypical protein kinase-like fold to enable coenzyme Q biosynthesis

The ancient UbiB protein kinase-like family is involved in isoprenoid lipid biosynthesis and is implicated in human diseases, but demonstration of UbiB kinase activity has remained elusive for unknown reasons. Here, we quantitatively define UbiB-specific sequence motifs and reveal their positions wi...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Stefely, Jonathan A., Reidenbach, Andrew G., Ulbrich, Arne, Oruganty, Krishnadev, Floyd, Brendan J., Jochem, Adam, Saunders, Jaclyn M., Johnson, Isabel E., Minogue, Catherine E., Wrobel, Russell L., Barber, Grant E., Lee, David, Li, Sheng, Kannan, Natarajan, Coon, Joshua J., Bingman, Craig A., Pagliarini, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289473/
https://ncbi.nlm.nih.gov/pubmed/25498144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.11.002
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