Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis

Coenzyme Q (CoQ) is an isoprenylated quinone that is essential for cellular respiration and is synthesized in mitochondria by the combined action of at least nine proteins (COQ1–9). Although most COQ proteins are known to catalyze modifications to CoQ precursors, the biochemical role of COQ9 remains...

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發表在:Proc Natl Acad Sci U S A
Main Authors: Lohman, Danielle C., Forouhar, Farhad, Beebe, Emily T., Stefely, Matthew S., Minogue, Catherine E., Ulbrich, Arne, Stefely, Jonathan A., Sukumar, Shravan, Luna-Sánchez, Marta, Jochem, Adam, Lew, Scott, Seetharaman, Jayaraman, Xiao, Rong, Wang, Huang, Westphall, Michael S., Wrobel, Russell L., Everett, John K., Mitchell, Julie C., López, Luis C., Coon, Joshua J., Tong, Liang, Pagliarini, David J.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2014
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PNAS Plus
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226113/
https://ncbi.nlm.nih.gov/pubmed/25339443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413128111
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