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Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis

Coenzyme Q (CoQ) is an isoprenylated quinone that is essential for cellular respiration and is synthesized in mitochondria by the combined action of at least nine proteins (COQ1–9). Although most COQ proteins are known to catalyze modifications to CoQ precursors, the biochemical role of COQ9 remains...

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Publicado en:Proc Natl Acad Sci U S A
Main Authors: Lohman, Danielle C., Forouhar, Farhad, Beebe, Emily T., Stefely, Matthew S., Minogue, Catherine E., Ulbrich, Arne, Stefely, Jonathan A., Sukumar, Shravan, Luna-Sánchez, Marta, Jochem, Adam, Lew, Scott, Seetharaman, Jayaraman, Xiao, Rong, Wang, Huang, Westphall, Michael S., Wrobel, Russell L., Everett, John K., Mitchell, Julie C., López, Luis C., Coon, Joshua J., Tong, Liang, Pagliarini, David J.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226113/
https://ncbi.nlm.nih.gov/pubmed/25339443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413128111
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