Triple negative breast cancers express receptors for LHRH and are potential therapeutic targets for cytotoxic LHRH-analogs, AEZS 108 and AEZS 125

BACKGROUND: Triple negative breast cancer (TNBC) is a distinct subtype of breast cancer burdened with a dismal prognosis due to the lack of effective therapeutic agents. Receptors for LHRH (luteinizing hormone-releasing hormone) can be successfully targeted with AEZS-108 [AN-152], an analog of LHRH...

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Pubblicato in:BMC Cancer
Autori principali: Seitz, Stephan, Buchholz, Stefan, Schally, Andrew Victor, Weber, Florian, Klinkhammer-Schalke, Monika, Inwald, Elisabeth C, Perez, Roberto, Rick, Ferenc G, Szalontay, Luca, Hohla, Florian, Segerer, Sabine, Kwok, Chui Wai, Ortmann, Olaf, Engel, Jörg Bernhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289186/
https://ncbi.nlm.nih.gov/pubmed/25410881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-847
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