The targeted LHRH analog AEZS-108 alters expression of genes related to angiogenesis and development of metastasis in uveal melanoma

Uveal melanoma (UM) is the most common malignant tumor of the eye. Recently, we have established that 46% of UM specimens express LHRH receptors. This finding supports the idea of a LHRH receptor-targeted therapy of UM patients. Cytotoxic analog of LHRH, AEZS-108 exhibits effective anti-cancer activ...

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Vydáno v:Oncotarget
Hlavní autoři: Fodor, Klara, Dobos, Nikoletta, Schally, Andrew, Steiber, Zita, Olah, Gabor, Sipos, Eva, Szekvolgyi, Lorant, Halmos, Gabor
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6968782/
https://ncbi.nlm.nih.gov/pubmed/32010430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27431
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