The targeted LHRH analog AEZS-108 alters expression of genes related to angiogenesis and development of metastasis in uveal melanoma

Uveal melanoma (UM) is the most common malignant tumor of the eye. Recently, we have established that 46% of UM specimens express LHRH receptors. This finding supports the idea of a LHRH receptor-targeted therapy of UM patients. Cytotoxic analog of LHRH, AEZS-108 exhibits effective anti-cancer activ...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Fodor, Klara, Dobos, Nikoletta, Schally, Andrew, Steiber, Zita, Olah, Gabor, Sipos, Eva, Szekvolgyi, Lorant, Halmos, Gabor
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2020
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6968782/
https://ncbi.nlm.nih.gov/pubmed/32010430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27431
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