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Receptor-targeted therapy of human experimental urinary bladder cancers with cytotoxic LH-RH analog AN-152 (AEZS-108)

Many bladder cancers progress to invasion with poor prognosis; new therapeutic methods are needed. We developed a cytotoxic LH-RH analog, AN-152 (AEZS-108) containing doxorubicin (DOX), for targeted therapy of cancers expressing LHRH receptors. We investigated the expression of LH-RH receptors in cl...

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Detalhes bibliográficos
Main Authors: Szepeshazi, Karoly, Schally, Andrew V., Keller, Gunhild, Block, Norman L., Benten, Daniel, Halmos, Gabor, Szalontay, Luca, Vidaurre, Irving, Jaszberenyi, Miklos, Rick, Ferenc G.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443252/
https://ncbi.nlm.nih.gov/pubmed/22824624
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