Interaction between Calpain-1 and HSP90: New Insights into the Regulation of Localization and Activity of the Protease

Here we demonstrate that heat shock protein 90 (HSP90) interacts with calpain-1, but not with calpain-2, and forms a discrete complex in which the protease maintains its catalytic activity, although with a lower affinity for Ca(2+). Equilibrium gel distribution experiments show that this complex is...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS One
मुख्य लेखकों: Averna, Monica, De Tullio, Roberta, Pedrazzi, Marco, Bavestrello, Margherita, Pellegrini, Matteo, Salamino, Franca, Pontremoli, Sandro, Melloni, Edon
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2015
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289065/
https://ncbi.nlm.nih.gov/pubmed/25575026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116738
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन