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A review and re-interpretation of a group-sequential approach to sample size re-estimation in two-stage trials
In this paper, we review the adaptive design methodology of Li et al. (Biostatistics 3:277–287) for two-stage trials with mid-trial sample size adjustment. We argue that it is closer in principle to a group sequential design, in spite of its obvious adaptive element. Several extensions are proposed...
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| Udgivet i: | Pharm Stat |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BlackWell Publishing Ltd
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4288989/ https://ncbi.nlm.nih.gov/pubmed/24692348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pst.1613 |
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