Mucosal Immunization with the Live Attenuated Vaccine SPY1 Induces Humoral and Th2-Th17-Regulatory T Cell Cellular Immunity and Protects against Pneumococcal Infection

Mucosal immunization with attenuated vaccine can protect against pneumococcal invasion infection, but the mechanism was unknown. Our study found that mucosal delivery with the live attenuated SPY1 vaccine strain can confer T cell- and B cell-dependent protection against pneumococcal colonization and...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Infect Immun
Κύριοι συγγραφείς: Xu, Xiuyu, Wang, Hong, Liu, Yusi, Wang, Yiping, Zeng, Lingbing, Wu, Kaifeng, Wang, Jianmin, Ma, Feng, Xu, Wenchun, Yin, Yibing, Zhang, Xuemei
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2014
Θέματα:
Microbial Immunity and Vaccines
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288905/
https://ncbi.nlm.nih.gov/pubmed/25312946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02334-14
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