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Enhancing the efficiency of direct reprogramming of human primary fibroblasts into dopaminergic neuron-like cells through p53 suppression
Dopaminergic (DA) neuron-like cells obtained through direct reprogramming of primary human fibroblasts offer exciting opportunities for treatment of Parkinson’s disease. A significant obstacle is the low efficiency of conversion during the reprogramming process. Here, we demonstrate that the suppres...
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| Publicado no: | Sci China Life Sci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4288576/ https://ncbi.nlm.nih.gov/pubmed/25129808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11427-014-4730-2 |
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