Efficient Reprogramming of Mouse Fibroblasts to Neuronal Cells including Dopaminergic Neurons

Somatic cells were directly converted to functional neurons through the use of a combination of transcription factors, including Ascl1, Brn2, and Myt1l. However, a major limitation is the lack of a reliable source of cell-replacement therapy for neurological diseases. Here, we show that a combinatio...

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Main Authors: Oh, Seung-ick, Park, Hang-soo, Hwang, Insik, Park, Han-kyul, Choi, Kyung-Ah, Jeong, Hyesun, Kim, Suhng Wook, Hong, Sunghoi
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058809/
https://ncbi.nlm.nih.gov/pubmed/24991651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/957548
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