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Generation of Functional Dopaminergic Neurons from Reprogramming Fibroblasts by Nonviral-based Mesoporous Silica Nanoparticles

Direct-lineage conversion of the somatic cell by reprogramming, in which mature cells were fully converted into a variety of other cell types bypassing an intermediate pluripotent state, is a promising regenerative medicine approach. Due to the risk of tumorigenesis by viral methods, a non-viral car...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chang, Jen-Hsuan, Tsai, Ping-Hsing, Wang, Kai-Yi, Wei, Yu-Ting, Chiou, Shih-Hwa, Mou, Chung-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758610/
https://ncbi.nlm.nih.gov/pubmed/29311646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18324-8
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