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The mTOR signaling pathway as a treatment target for intracranial neoplasms

Inhibition of the mammalian target of rapamycin (mTOR) signaling pathway has become an attractive target for human cancer therapy. Hyperactivation of mTOR has been reported in both sporadic and syndromic (hereditary) brain tumors. In contrast to the large number of successful clinical trials employi...

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Bibliografiska uppgifter
I publikationen:Neuro Oncol
Huvudupphovsmän: Pachow, Doreen, Wick, Wolfgang, Gutmann, David H., Mawrin, Christian
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288522/
https://ncbi.nlm.nih.gov/pubmed/25165193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou164
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