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BMP-9 regulates the osteoblastic differentiation and calcification of vascular smooth muscle cells through an ALK1 mediated pathway

The process of vascular calcification shares many similarities with that of physiological skeletal mineralization, and involves the deposition of hydroxyapatite crystals in arteries. However, the cellular mechanisms responsible have yet to be fully explained. Bone morphogenetic protein (BMP-9) has b...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Zhu, Dongxing, Mackenzie, Neil Charles Wallace, Shanahan, Catherine M, Shroff, Rukshana C, Farquharson, Colin, MacRae, Vicky Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288360/
https://ncbi.nlm.nih.gov/pubmed/25297851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12373
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