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BMP-9 regulates the osteoblastic differentiation and calcification of vascular smooth muscle cells through an ALK1 mediated pathway

The process of vascular calcification shares many similarities with that of physiological skeletal mineralization, and involves the deposition of hydroxyapatite crystals in arteries. However, the cellular mechanisms responsible have yet to be fully explained. Bone morphogenetic protein (BMP-9) has b...

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Dettagli Bibliografici
Pubblicato in:J Cell Mol Med
Autori principali: Zhu, Dongxing, Mackenzie, Neil Charles Wallace, Shanahan, Catherine M, Shroff, Rukshana C, Farquharson, Colin, MacRae, Vicky Elizabeth
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288360/
https://ncbi.nlm.nih.gov/pubmed/25297851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12373
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