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Regulation of anti-sense transcription by Mot1p and NC2 via removal of TATA-binding protein (TBP) from the 3′-end of genes

The activity and dynamic nature of TATA-binding protein (TBP) crucial to RNA polymerase II-mediated transcription is under control of the Mot1p and NC2 complexes. Here we show that both TBP regulatory factors play ‘hidden’ roles in ensuring transcription fidelity by restricting anti-sense non-coding...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Koster, Maria J.E., Timmers, H.Th. Marc
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288163/
https://ncbi.nlm.nih.gov/pubmed/25432956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1263
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