Cooperative action of NC2 and Mot1p to regulate TATA-binding protein function across the genome

Promoter recognition by TATA-binding protein (TBP) is an essential step in the initiation of RNA polymerase II (pol II) mediated transcription. Genetic and biochemical studies in yeast have shown that Mot1p and NC2 play important roles in inhibiting TBP activity. To understand how TBP activity is re...

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Detalhes bibliográficos
Main Authors: van Werven, Folkert J., van Bakel, Harm, van Teeffelen, Hetty A.A.M., Altelaar, A.F. Maarten, Koerkamp, Marian Groot, Heck, Albert J.R., Holstege, Frank C.P., Timmers, H.Th. Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532931/
https://ncbi.nlm.nih.gov/pubmed/18703679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1682308
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