A Drosophila model of FUS-related neurodegeneration reveals genetic interaction between FUS and TDP-43

Amyotrophic lateral sclerosis (ALS) is a late-onset neurodegenerative disorder characterized by the loss of motor neurons. Fused in sarcoma/translated in liposarcoma (FUS/TLS) and TAR DNA-binding protein (TDP)-43 are DNA/RNA-binding proteins found to be mutated in sporadic and familial forms of ALS....

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Pubblicato in:Hum Mol Genet
Autori principali: Lanson, Nicholas A., Maltare, Astha, King, Hanna, Smith, Rebecca, Kim, Ji Han, Taylor, J. Paul, Lloyd, Thomas E., Pandey, Udai Bhan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288133/
https://ncbi.nlm.nih.gov/pubmed/21487023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr150
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