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Synaptic Paths to Neurodegeneration: The Emerging Role of TDP-43 and FUS in Synaptic Functions

TAR DNA-binding protein-43 KDa (TDP-43) and fused in sarcoma (FUS) as the defining pathological hallmarks for amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), coupled with ALS-FTD-causing mutations in both genes, indicate that their dysfunctions damage the motor system and cogn...

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Detalhes bibliográficos
Publicado no:Neural Plast
Autor principal: Ling, Shuo-Chien
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5925147/
https://ncbi.nlm.nih.gov/pubmed/29755516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/8413496
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