5-azacytidine inhibits nonsense-mediated decay in a MYC-dependent fashion

Nonsense-mediated RNA decay (NMD) is an RNA-based quality control mechanism that eliminates transcripts bearing premature translation termination codons (PTC). Approximately, one-third of all inherited disorders and some forms of cancer are caused by nonsense or frame shift mutations that introduce...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Bhuvanagiri, Madhuri, Lewis, Joe, Putzker, Kerstin, Becker, Jonas P, Leicht, Stefan, Krijgsveld, Jeroen, Batra, Richa, Turnwald, Brad, Jovanovic, Bogdan, Hauer, Christian, Sieber, Jana, Hentze, Matthias W, Kulozik, Andreas E
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287977/
https://ncbi.nlm.nih.gov/pubmed/25319547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404461
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados