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Cooperative subunit interactions mediate fast C-type inactivation of hERG1 K(+) channels
At depolarized membrane potentials, the conductance of some voltage-gated K(+) channels is reduced by C-type inactivation. This gating process is voltage independent in K(v)1 and involves a conformational change in the selectivity filter that is mediated by cooperative subunit interactions. C-type i...
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| Udgivet i: | J Physiol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science Inc
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4287738/ https://ncbi.nlm.nih.gov/pubmed/25063820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.277483 |
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