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Systematic exploration of guide-tree topology effects for small protein alignments

BACKGROUND: Guide-trees are used as part of an essential heuristic to enable the calculation of multiple sequence alignments. They have been the focus of much method development but there has been little effort at determining systematically, which guide-trees, if any, give the best alignments. Some...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Sievers, Fabian, Hughes, Graham M, Higgins, Desmond G
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287568/
https://ncbi.nlm.nih.gov/pubmed/25282640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-338
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