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Systematic exploration of guide-tree topology effects for small protein alignments

BACKGROUND: Guide-trees are used as part of an essential heuristic to enable the calculation of multiple sequence alignments. They have been the focus of much method development but there has been little effort at determining systematically, which guide-trees, if any, give the best alignments. Some...

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Publicat a:BMC Bioinformatics
Autors principals: Sievers, Fabian, Hughes, Graham M, Higgins, Desmond G
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287568/
https://ncbi.nlm.nih.gov/pubmed/25282640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-338
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