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Systematic exploration of guide-tree topology effects for small protein alignments

BACKGROUND: Guide-trees are used as part of an essential heuristic to enable the calculation of multiple sequence alignments. They have been the focus of much method development but there has been little effort at determining systematically, which guide-trees, if any, give the best alignments. Some...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Sievers, Fabian, Hughes, Graham M, Higgins, Desmond G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287568/
https://ncbi.nlm.nih.gov/pubmed/25282640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-338
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