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Identification of Constrained Cancer Driver Genes Based on Mutation Timing
Cancer drivers are genomic alterations that provide cells containing them with a selective advantage over their local competitors, whereas neutral passengers do not change the somatic fitness of cells. Cancer-driving mutations are usually discriminated from passenger mutations by their higher degree...
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| Publicado no: | PLoS Comput Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4287396/ https://ncbi.nlm.nih.gov/pubmed/25569148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004027 |
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