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Frequent co-amplification and co-operation between C-MYC and PVT1 oncogenes promote malignant pleural mesothelioma
INTRODUCTION: Malignant pleural mesothelioma (MPM) is a deadly disease with poor prognosis and few treatment options. We characterized and elucidate the roles of C-MYC and PVT1 involved in the pathogenesis of MPM. METHODS: We used siRNA-mediated knockdown in MPM cell lines to determine the effect of...
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| Publicado no: | J Thorac Oncol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4287384/ https://ncbi.nlm.nih.gov/pubmed/24926545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000202 |
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