The Hypoxic Response Contributes to Altered Gene Expression and Pre-Capillary Pulmonary Hypertension in Patients with Sickle Cell Disease

BACKGROUND: We postulated that the hypoxic response in sickle cell disease (SCD) contributes to altered gene expression and pulmonary hypertension, a complication associated with early mortality. METHODS AND RESULTS: To identify genes regulated by the hypoxic response and not other effects of chroni...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Circulation
Autores principales: Zhang, Xu, Zhang, Wei, Ma, Shwu-Fan, Desai, Ankit A., Saraf, Santosh, Miasniakova, Galina, Sergueeva, Adelina, Ammosova, Tatiana, Xu, Min, Nekhai, Sergei, Abbasi, Taimur, Casanova, Nancy G., Steinberg, Martin H., Baldwin, Clinton T., Sebastiani, Paola, Prchal, Josef T., Kittles, Rick, Garcia, Joe G. N., Machado, Roberto F., Gordeuk, Victor R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287376/
https://ncbi.nlm.nih.gov/pubmed/24515990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.113.005296
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares