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Hemodynamic effects and histamine release elicited by the selective adenosine A(3) receptor agonist 2-Cl-IB-MECA in conscious rats

The hemodynamic effects of the novel, selective adenosine A(3) receptor agonist 2-chloro-N(6)-(3-iodobenzyl)adenosine-5′-N-methyl-carboxamide (2-Cl-IB-MECA) were investigated in conscious rats. Intravenous administration of 200 μg/kg 2-Cl-IB-MECA resulted in a short-lasting hypotension, which was ac...

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Detalhes bibliográficos
Publicado no:Eur J Pharmacol
Main Authors: Van Schaick, Erno A., Jacobson, Kenneth A., Kim, Hea O., IJzerman, Adriaan P., Danhof, Meindert
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287249/
https://ncbi.nlm.nih.gov/pubmed/8858305
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