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Ablation of the Glucagon Receptor Gene Increases Fetal Lethality and Produces Alterations in Islet Development and Maturation
Although glucagon (GLU) plays a pivotal role in glucose homeostasis, its role in the regulation of fetal growth and maturation is poorly understood. These issues were examined in a line of mice with a global deletion of the GLU receptor (Gcgr(−/−)), which are characterized by lower blood glucose lev...
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| Vydáno v: | Endocrinology |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4287247/ https://ncbi.nlm.nih.gov/pubmed/16627579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2005-1410 |
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