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Mouse Insulin Cells Expressing an Inducible RIPCre Transgene Are Functionally Impaired

We used cre-lox technology to test whether the inducible expression of Cre minimize the deleterious effect of the enzyme on beta cell function. We studied mice in which Cre is linked to a modified estrogen receptor (ER), and its expression is controlled by the rat insulin promoter (RIP). Following t...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Teitelman, Gladys, Kedees, Mamdouh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319030/
https://ncbi.nlm.nih.gov/pubmed/25533471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.615484
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