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DBC1/CCAR2 and CCAR1 Are Largely Disordered Proteins that Have Evolved from One Common Ancestor

Deleted in breast cancer 1 (DBC1, CCAR2, KIAA1967) is a large, predominantly nuclear, multidomain protein that modulates gene expression by inhibiting several epigenetic modifiers, including the deacetylases SIRT1 and HDAC3, and the methyltransferase SUV39H1. DBC1 shares many highly conserved protei...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Brunquell, Jessica, Yuan, Jia, Erwin, Aqeela, Westerheide, Sandy D., Xue, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287135/
https://ncbi.nlm.nih.gov/pubmed/25610865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/418458
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