Combination MET inhibition and Topoisomerase I inhibition block cell growth of Small Cell Lung Cancer

Small cell lung cancer (SCLC) is a devastating disease, and current therapies have not greatly improved the 5-year survival rates. Topoisomerase (Top) inhibition is a treatment modality for SCLC; however, the response is short lived. Consequently, our research has focused on improving SCLC therapeut...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Rolle, Cleo E., Kanteti, Rajani, Surati, Mosmi, Nandi, Suvobroto, Dhanasingh, Immanuel, Yala, Soheil, Tretiakova, Maria, Arif, Qudsia, Hembrough, Todd, Brand, Toni M., Wheeler, Deric L., Husain, Aliya N., Vokes, Everett E., Bharti, Ajit, Salgia, Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286701/
https://ncbi.nlm.nih.gov/pubmed/24327519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0109
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