Combination MET inhibition and Topoisomerase I inhibition block cell growth of Small Cell Lung Cancer

Small cell lung cancer (SCLC) is a devastating disease, and current therapies have not greatly improved the 5-year survival rates. Topoisomerase (Top) inhibition is a treatment modality for SCLC; however, the response is short lived. Consequently, our research has focused on improving SCLC therapeut...

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Udgivet i:Mol Cancer Ther
Main Authors: Rolle, Cleo E., Kanteti, Rajani, Surati, Mosmi, Nandi, Suvobroto, Dhanasingh, Immanuel, Yala, Soheil, Tretiakova, Maria, Arif, Qudsia, Hembrough, Todd, Brand, Toni M., Wheeler, Deric L., Husain, Aliya N., Vokes, Everett E., Bharti, Ajit, Salgia, Ravi
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286701/
https://ncbi.nlm.nih.gov/pubmed/24327519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0109
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