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Combination MET inhibition and Topoisomerase I inhibition block cell growth of Small Cell Lung Cancer

Small cell lung cancer (SCLC) is a devastating disease, and current therapies have not greatly improved the 5-year survival rates. Topoisomerase (Top) inhibition is a treatment modality for SCLC; however, the response is short lived. Consequently, our research has focused on improving SCLC therapeut...

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發表在:Mol Cancer Ther
Main Authors: Rolle, Cleo E., Kanteti, Rajani, Surati, Mosmi, Nandi, Suvobroto, Dhanasingh, Immanuel, Yala, Soheil, Tretiakova, Maria, Arif, Qudsia, Hembrough, Todd, Brand, Toni M., Wheeler, Deric L., Husain, Aliya N., Vokes, Everett E., Bharti, Ajit, Salgia, Ravi
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286701/
https://ncbi.nlm.nih.gov/pubmed/24327519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0109
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