Role of PAX8 in the regulation of MET and RON receptor tyrosine kinases in non-small cell lung cancer

BACKGROUND: Non-small cell lung cancers (NSCLC) are highly heterogeneous at the molecular level and comprise 75% of all lung tumors. We have previously shown that the receptor tyrosine kinase (RTK) MET frequently suffers gain-of-function mutations that significantly promote lung tumorigenesis. Subse...

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Hlavní autoři: Kanteti, Rajani, El-Hashani, Essam, Dhanasingh, Immanuel, Tretiakova, Maria, Husain, Aliya N, Sharma, Sherven, Sharma, Jay, Vokes, Everett E, Salgia, Ravi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995599/
https://ncbi.nlm.nih.gov/pubmed/24628993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-185
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