Antiangiogenic Effects of Topically Administered Multiple Kinase Inhibitor, Motesanib (AMG 706), on Experimental Choroidal Neovascularization in Mice

Purpose: To investigate the effect of topical motesanib, an inhibitor of receptor tyrosine kinase, on experimental choroidal neovascularization (CNV). Methods: CNV was induced in 46 nine-week-old male C57BL/6 mice using fundus laser photocoagulation. The right eye of each mouse was treated with mote...

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Veröffentlicht in:J Ocul Pharmacol Ther
Hauptverfasser: Rho, Chang Rae, Kang, Seungbum, Park, Ki Cheol, Yang, Keum-Jin, Choi, Hyunsu, Cho, Won-Kyung
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2015
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286588/
https://ncbi.nlm.nih.gov/pubmed/25255037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2014.0023
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