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TCR and CD28 activate the transcription factor NF-κB in T-cells via distinct adaptor signaling complexes
The transcription factor NF-κB is needed for the induction of inflammatory responses in T-cells. Whether its activation by the antigen-receptor and CD28 is mediated by the same or different intracellular signaling pathways has been unclear. Here, using T-cells from various knock-out (Cd28(−/−), adap...
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| Udgivet i: | Immunol Lett |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier/North-Holland Biomedical Press
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4286576/ https://ncbi.nlm.nih.gov/pubmed/25455592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2014.10.020 |
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