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Phosphorylation of Carma1, but not Bcl10, by Akt regulates TCR/CD28-mediated NF-κB induction and cytokine production

Previous studies from our group and others have shown that the Akt kinase can contribute to induction of NF-κB by antigen receptor signaling. However, the direct targets of Akt in this pathway are not known. Here we show that Akt-mediated NF-κB activation is mediated at least in part through direct...

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Bibliografische gegevens
Hoofdauteurs: Cheng, Jing, Hamilton, Kristia S., Kane, Lawrence P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968090/
https://ncbi.nlm.nih.gov/pubmed/24548923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2014.01.011
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