Resveratrol induces apoptosis by directly targeting Ras-GTPase activating protein SH3 domain binding protein 1 (G3BP1)

Resveratrol possesses a strong anticancer activity exhibited as the induction of apoptosis through p53 activation. However, the molecular mechanism and direct target(s) of resveratrol-induced p53 activation remain elusive. Here, the Ras-GTPase activating protein SH3 domain binding protein 1 (G3BP1)...

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Udgivet i:Oncogene
Main Authors: Oi, Naomi, Yuan, Jian, Malakhova, Margarita, Luo, Kuntian, Li, Yunhui, Ryu, Joohyun, Zhang, Lei, Bode, Ann M., Xu, Zengguang, Li, Yan, Lou, Zhenkun, Dong, Zigang
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286533/
https://ncbi.nlm.nih.gov/pubmed/24998844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.194
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