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Congenital leptin deficiency: diagnosis and effects of leptin replacement therapy
To describe our 10-year experience in treating leptin-deficient humans. Three adults and one boy presented with childhood-onset morbid obesity, hypogonadism and family history of obesity and early death. Serum leptin was inappropriately low. A recessive C105T leptin gene mutation was identified. Met...
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| Pubblicato in: | Arq Bras Endocrinol Metabol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4286252/ https://ncbi.nlm.nih.gov/pubmed/21340154 |
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