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A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer

Complex focal chromosomal rearrangements in cancer genomes, also called “firestorms”, can be scored from DNA copy number data. The complex arm‐wise aberration index (CAAI) is a score that captures DNA copy number alterations that appear as focal complex events in tumors, and has potential prognostic...

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Veröffentlicht in:Mol Oncol
Hauptverfasser: Vollan, Hans Kristian Moen, Rueda, Oscar M., Chin, Suet-Feung, Curtis, Christina, Turashvili, Gulisa, Shah, Sohrab, Lingjærde, Ole Christian, Yuan, Yinyin, Ng, Charlotte K., Dunning, Mark J., Dicks, Ed, Provenzano, Elena, Sammut, Stephen, McKinney, Steven, Ellis, Ian O., Pinder, Sarah, Purushotham, Arnie, Murphy, Leigh C., Kristensen, Vessela N., Brenton, James D., Pharoah, Paul D.P., Børresen-Dale, Anne-Lise, Aparicio, Samuel, Caldas, Carlos
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286124/
https://ncbi.nlm.nih.gov/pubmed/25169931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.07.019
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