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Enforced telomere elongation increases the sensitivity of human tumour cells to ionizing radiation
More than 85% of all human cancers possess the ability to maintain chromosome ends, or telomeres, by virtue of telomerase activity. Loss of functional telomeres is incompatible with survival, and telomerase inhibition has been established in several model systems to be a tractable target for cancer...
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| Publicado no: | DNA Repair (Amst) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4286114/ https://ncbi.nlm.nih.gov/pubmed/25484304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.11.005 |
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