Vitamin D Nuclear Receptor Deficiency Promotes Cholestatic Liver Injury by Disruption of Biliary Epithelial Cell Junctions in Mice

Alterations in apical junctional complexes (AJCs) have been reported in genetic or acquired biliary diseases. The vitamin D nuclear receptor (VDR), predominantly expressed in biliary epithelial cells in the liver, has been shown to regulate AJCs. The aim of our study was thus to investigate the role...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Firrincieli, Delphine, Zúñiga, Silvia, Rey, Colette, Wendum, Dominique, Lasnier, Elisabeth, Rainteau, Dominique, Braescu, Thomas, Falguières, Thomas, Boissan, Mathieu, Cadoret, Axelle, Housset, Chantal, Chignard, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2013
Assuntos:
Autoimmune, Cholestatic and Biliary Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286017/
https://ncbi.nlm.nih.gov/pubmed/23696511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26453
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