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Effects of food on the pharmacokinetics of ponatinib in healthy subjects
WHAT IS KNOWN AND OBJECTIVE: Ponatinib is a potent oral tyrosine kinase inhibitor with activity against BCR-ABL, the primary driver of chronic myeloid leukaemia and Philadelphia chromosome–positive acute lymphoblastic leukaemia. This single-centre, single-dose, randomized, open-label, three-period c...
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Publicado no: | J Clin Pharm Ther |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BlackWell Publishing Ltd
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4286001/ https://ncbi.nlm.nih.gov/pubmed/23888935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcpt.12082 |
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