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Enantioselective Synthesis of α-Secondary and α-Tertiary Piperazin-2-ones and Piperazines by Catalytic Asymmetric Allylic Alkylation

The asymmetric Pd-catalyzed decarboxylative allylic alkylation of differentially N-protected piperazin-2-ones allows for the synthesis of a variety of highly enantioenriched tertiary piperazine-2-ones. Deprotection and reduction affords the corresponding tertiary piperazines, which can be employed f...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Angew Chem Int Ed Engl
मुख्य लेखकों: Korch, Katerina M., Eidamshaus, Christian, Behenna, Douglas C., Nam, Sangkil, Horne, David, Stoltz, Brian M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285707/
https://ncbi.nlm.nih.gov/pubmed/25382664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201408609
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