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Principles of ER coranslational translocation revealed by proximity-specific ribosome profiling
Localized protein synthesis is a fundamental mechanism for creating distinct subcellular environments. Here we developed a generalizable proximity-specific ribosome profiling strategy that enables global analysis of translation in defined subcellular locations. We applied this approach to the endopl...
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| Pubblicato in: | Science |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4285348/ https://ncbi.nlm.nih.gov/pubmed/25378630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1257521 |
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