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Biochemical comparison of four commercially available C1 esterase inhibitor concentrates for treatment of hereditary angioedema

BACKGROUND: For safe and efficacious treatment of hereditary angioedema, C1 esterase inhibitor (C1-INH) concentrates should have high purity and high amounts of functional protein. As no pharmacopoeia requirements exist for C1-INH concentrate lot release, biochemical characteristics as declared by t...

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Publicat a:Transfusion
Autors principals: Feussner, Annette, Kalina, Uwe, Hofmann, Peter, Machnig, Thomas, Henkel, Georg
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285325/
https://ncbi.nlm.nih.gov/pubmed/24805006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/trf.12678
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